Objective:
Replication
1. Evaluate the contributions of scientists to the discovery of DNA.
2. Apply the base-pairing rule to the structure of DNA and RNA.
3. Identify the monomers of Nucleic Acids, as well as the basic structure of a nucleic acid polymer.
4. Summarize the steps of DNA Replication and where it occurs in the cell (Honors - understand the order and purpose of enzymes associated with the process).
5. Understand the concepts of 5'-3' and 5'-3', and understand why one strand is being synthesized backwards.
6. Discuss the purpose of DNA replication, and where this stage belongs in the cell cycle.
Protein Synthesis - Transcription
7. Compare and contrast the three types of RNA (mRNA, tRNA, and rRNA)
8. Compare and contrast DNA and RNA
9. Discuss the stages of transcription, and the relationship between DNA and mRNA during this process
10. Understand the end result of transcription, and where the mRNA goes after this process
11. Understand the process of mRNA splicing and its purpose (H)
Protein Synthesis - Translation
12. Explain the relationship between mRNA, tRNA, the ribosome and amino acids in the process of translation
13. Understand that only one gene is being translated at a time in this process
14. Understand that amino acids bond through the peptide bonds discussed in Unit 1 (biomolecules)
15. Understand that the end result of translation is a chain of amino acids that must be folded in order to be functional.
Mutations
16. Discuss how gene mutations - silent, missense, nonsense, frameshift, addition and deletion - can affect the functionality of a protein.
17. Understand what can cause mutations (Internal and external)
18. Compare and contrast gene mutations and chromosome mutations
Help videos
DNA Structure
The Structure of DNA (including primes)
Structure of DNA (and anti-parallel)
What is a gene?
Replication
DNA Replication (Amoeba Sisters-A)
DNA Replication (Bozeman Science -H)
Protein Synthesis
Three types of RNA (Amoeba sisters -A)
Three types of RNA
Overview of Protein Synthesis
Protein Synthesis (Amoeba sisters -A)
Protein Synthesis (Bozeman Science -H)
Mutations
Mutations (Amoeba sisters -A)
Mutations (Bozeman Science -H)
Practice - Unit 2 - Protein Synthesis
Practice - Unit 2 - Protein Synthesis (key)
Replication
1. Evaluate the contributions of scientists to the discovery of DNA.
2. Apply the base-pairing rule to the structure of DNA and RNA.
3. Identify the monomers of Nucleic Acids, as well as the basic structure of a nucleic acid polymer.
4. Summarize the steps of DNA Replication and where it occurs in the cell (Honors - understand the order and purpose of enzymes associated with the process).
5. Understand the concepts of 5'-3' and 5'-3', and understand why one strand is being synthesized backwards.
6. Discuss the purpose of DNA replication, and where this stage belongs in the cell cycle.
Protein Synthesis - Transcription
7. Compare and contrast the three types of RNA (mRNA, tRNA, and rRNA)
8. Compare and contrast DNA and RNA
9. Discuss the stages of transcription, and the relationship between DNA and mRNA during this process
10. Understand the end result of transcription, and where the mRNA goes after this process
11. Understand the process of mRNA splicing and its purpose (H)
Protein Synthesis - Translation
12. Explain the relationship between mRNA, tRNA, the ribosome and amino acids in the process of translation
13. Understand that only one gene is being translated at a time in this process
14. Understand that amino acids bond through the peptide bonds discussed in Unit 1 (biomolecules)
15. Understand that the end result of translation is a chain of amino acids that must be folded in order to be functional.
Mutations
16. Discuss how gene mutations - silent, missense, nonsense, frameshift, addition and deletion - can affect the functionality of a protein.
17. Understand what can cause mutations (Internal and external)
18. Compare and contrast gene mutations and chromosome mutations
Help videos
DNA Structure
The Structure of DNA (including primes)
Structure of DNA (and anti-parallel)
What is a gene?
Replication
DNA Replication (Amoeba Sisters-A)
DNA Replication (Bozeman Science -H)
Protein Synthesis
Three types of RNA (Amoeba sisters -A)
Three types of RNA
Overview of Protein Synthesis
Protein Synthesis (Amoeba sisters -A)
Protein Synthesis (Bozeman Science -H)
Mutations
Mutations (Amoeba sisters -A)
Mutations (Bozeman Science -H)
Practice - Unit 2 - Protein Synthesis
Practice - Unit 2 - Protein Synthesis (key)